Studies available for: Carotid Artery Disease

See a study that interests you? Contact that study's coordinator for more information on how to participate.


Study Information:
: SAPPHIRE WW: STENTING AND ANGIOPLASTY WITH PROTECTION IN PATIENTS AT HIGH-RISK FOR ENDARTERECTOMY
Houston, TX
Memorial Hermann Hospital, Heart and Vascular Institute, TMC,
The primary objective of this multi-center, prospective, observational study is to estimate 30-day MAE rate of stenting (any death, stroke or any MI) with distal protection in the treatment of obstructive carotid artery disease in high-surgical risk patients with atherosclerotic disease of the carotid artery(ies). The devices to be utilized are the Cordis PRECISEŅ Nitinol Stent Systems, the Cordis ANGIOGUARD™ XP/RX Emboli Capture Guidewire (ECGW) and next generation Cordis carotid stents and EPDs as they become commercially available. The secondary objectives are to assess the consistency of 30-day MAE rates of stenting with distal protection in the treatment of obstructive carotid artery disease at high, medium and low volume center with physicians who have validated CASES training levels of 1, 2, 2P or 3 (see appendix C) and to estimate 360-day MAE (death and ipsilateral stroke) rate.
HSC-MS-06-0497
Cordis – A J&J Co.
Subject Information:
>18yrs.
The primary objective of this multi-center, prospective, observational study is to estimate 30-day MAE rate of stenting (any death, stroke or any MI) with distal protection in the treatment of obstructive carotid artery disease in high-surgical risk patients with atherosclerotic disease of the carotid artery(ies). The devices to be utilized are the Cordis PRECISEŅ Nitinol Stent Systems, the Cordis ANGIOGUARD™ XP/RX Emboli Capture Guidewire (ECGW) and next generation Cordis carotid stents and EPDs as they become commercially available. The secondary objectives are to assess the consistency of 30-day MAE rates of stenting with distal protection in the treatment of obstructive carotid artery disease at high, medium and low volume center with
Study Coordinator(s) Information:
Mary Vooletich, RN
Mary.Vooletich@uth.tmc.edu
713-500-6550
Principal Investigator Information:
Dr. Rochard Smalling, MD, Ph.D